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TFAP

TFAP is a cell-permeable pyridinyl-benzamide compound that acts as a COX-1-selective inhibitor by targeting the enzyme's active site. TFAP displays analgesic properties in mice and rats in vivo without long-term cytotoxic effects. Unlike COX-2-inhibiting analgesics such as aspirin, TFAP is shown not to cause gastric damage in rats in vivo.

Product Specifications

CAS Number

1011244-68-0

Product Name Alternative

TFAP

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 155 mg/mL; 551.15 mM

Smiles

O=C (Nc1ccc (N) cn1) c2ccc (cc2) C (F) (F) F

Molecular Formula

C13H10F3N3O

Molecular Weight

281.23

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (5-amino-2-pyridinyl) -4- (trifluoromethyl) -benzamide

Available Sizes

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