Tomatine
Tomatine is a glycoalkaloid found in the tomato plant (Lycopersicon esculentum Mill.) . Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity.
Product Specifications
CAS Number
17406-45-0
Product Name Alternative
Lycopersicin
Purity
>98% (HPLC)
Solubility
DMSO:96.7 mM
Smiles
C[C@H]1[C@H]2[C@H] (C[C@H]3[C@@H]4CC[C@H]5C[C@H] (CC[C@]5 (C) [C@H]4CC[C@]23C) O[C@@H]2O[C@H] (CO) [C@H] (O[C@@H]3O[C@H] (CO) [C@@H] (O) [C@H] (O[C@@H]4OC[C@@H] (O) [C@H] (O) [C@H]4O) [C@H]3O[C@@H]3O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]3O) [C@H] (O) [C@H]2O) O[C@@]11CC[C@H] (C) CN1
Molecular Formula
C50H83NO21
Molecular Weight
1034.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(2S3R4S5S6R) -2- (((2S3R4S5R6R) -2- (((2R3R4R5R6R) -45-dihydroxy-2- (hydroxymethyl) -6- (((2aS4S5'S6aS6bS8aS8bR9S10S11aS12aS12bR) -5'6a8a9-tetramethyloctadecahydrospiro[naphtho[2'1':45]indeno[21-b]furan-102'-piperidin]-4-yl) oxy) tetrahydro-2H-pyran-3-yl) oxy) -5-hydroxy-6- (hydroxymethyl) -4- (((2S3R4S5R) -345-trihydroxytetrahydro-2H-pyran-2-yl) oxy) tetrahydro-2H-pyran-3-yl) oxy) -6- (hydroxymethyl) tetrahydro-2H-pyran-345-triol
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