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NVP-ADW742 b

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM >16-fold more potent against IGF-1R than InsR; little activity to HER2 PDGFR VEGFR-2 Bcr-Abl and c-Kit.

Product Specifications

CAS Number

475488-23-4

Product Name Alternative

ADW | GSK 552602A | ADW742

Purity

>98% (HPLC)

Solubility

DMSO:10 mg/mL (22.04 mM) warmed; Ethanol:3 mg/mL (6.61 mM) ; Water:<1 mg/mL

Smiles

C1CCN (C1) CC2CC (C2) N3C=C (C4=C3N=CN=C4N) C5=CC (=CC=C5) OCC6=CC=CC=C6

Molecular Formula

C28H31N5O

Molecular Weight

453.58

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5- (3- (benzyloxy) phenyl) -7- ((1r3r) -3- (pyrrolidin-1-ylmethyl) cyclobutyl) -7H-pyrrolo[23-d]pyrimidin-4-amine

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