Boc-MLF
Boc-MLF is a formyl peptide receptor (FPR) antagonist, and reduces superoxide production induced by fMLF with an IC50 of 0.63 μM[1].
Product Specifications
CAS Number
67247-12-5
Product Name Alternative
Boc-Met-Leu-Phe-OH
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Formyl Peptide Receptor (FPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/boc-mlf.html
Purity
99.93
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC(OC(C)(C)C)=O)=O)=O
Molecular Formula
C25H39N3O6S
Molecular Weight
509.66
Precautions
H302, H315, H319, H335
References & Citations
[1]Stenfeldt AL, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30 (6) :224-9. Epub 2007 Aug 9.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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