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Boc-MLF

Boc-MLF is a formyl peptide receptor (FPR) antagonist, and reduces superoxide production induced by fMLF with an IC50 of 0.63 μM[1].

Product Specifications

CAS Number

[67247-12-5]

Product Name Alternative

Boc-Met-Leu-Phe-OH

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Formyl Peptide Receptor (FPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/boc-mlf.html

Purity

99.93

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC(OC(C)(C)C)=O)=O)=O

Molecular Formula

C25H39N3O6S

Molecular Weight

509.66

Precautions

H302, H315, H319, H335

References & Citations

[1]Stenfeldt AL, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30 (6) :224-9. Epub 2007 Aug 9.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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