PD158780
PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR ErbB2 ErbB3 and ErbB4 (IC50s: 8μM 49 nM 52 nM and 52 nM in cell assay) .
Product Specifications
CAS Number
171179-06-9
Purity
>98% (HPLC)
Solubility
DMSO: 30 mg/mL (90.86 mM) ; Ethanol: 8 mg/mL (24.23 mM)
Smiles
CNc1cc2c (Nc3cccc (Br) c3) ncnc2cn1
Molecular Formula
C14H12BrN5
Molecular Weight
330.19
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-N- (3-bromophenyl) -6-N-methylpyrido[34-d]pyrimidine-46-diamine
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