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PD158780

PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR ErbB2 ErbB3 and ErbB4 (IC50s: 8μM 49 nM 52 nM and 52 nM in cell assay) .

Product Specifications

CAS Number

171179-06-9

Purity

>98% (HPLC)

Solubility

DMSO: 30 mg/mL (90.86 mM) ; Ethanol: 8 mg/mL (24.23 mM)

Smiles

CNc1cc2c (Nc3cccc (Br) c3) ncnc2cn1

Molecular Formula

C14H12BrN5

Molecular Weight

330.19

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4-N- (3-bromophenyl) -6-N-methylpyrido[34-d]pyrimidine-46-diamine

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