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HS-10296

Hs-10296 is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M which has only limited activity against wild-type EGFR.

Product Specifications

CAS Number

1899921-05-1

Purity

>98% (HPLC)

Solubility

DMSO:100 mg/mL (190.24 mM) ; Ethanol:6 mg/mL (11.41 mM) ; Water:Insoluble

Smiles

COc1cc (N (C) CCN (C) C) c (NC (=O) C=C) cc1Nc1nccc (n1) -c1cn (C2CC2) c2ccccc12

Molecular Formula

C30H35N7O2

Molecular Weight

525.66

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (5- ((4- (1-cyclopropyl-1H-indol-3-yl) pyrimidin-2-yl) amino) -2- ((2- (dimethylamino) ethyl) (methyl) amino) -4-methoxyphenyl) acrylamide

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