H-9 hydrochloride
H-9 hydrochloride inhibits PKA (Ki=1.9 μM), PKC (Ki=18 μM; cGKI (PKG) =0.87 μM; MLCK=70 μM) . It has shown to dramatically reduce the GABA response of GABAA currents in retinal rod bipolar cells as well as inhibit smooth muscle cell relaxation induced by cGRP. H-9 dihydrochloride has also been used for purification of protein kinases in ligand affinity chromatography.
Product Specifications
CAS Number
116970-50-4
Purity
>98% (HPLC)
Smiles
C1=CC2=C (C=CN=C2) C (=C1) S (=O) (=O) NCCN.Cl
Molecular Formula
C11H13N3O2S?HCl
Molecular Weight
287.77
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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