Myriocin
Myriocin, a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin strongly suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection.
Product Specifications
CAS Number
35891-70-4
Purity
>98% (HPLC)
Solubility
DMSO : 5 mg/mL (12.45 mM; ultrasonic and warming and heat to 60°C)
Smiles
CCCCCCC (CCCCCC/C=C/C[C@@H] (O) [C@H] (O) [C@] (CO) (N) C (O) =O) =O
Molecular Formula
C??H??NO?
Molecular Weight
401.54
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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