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SC-26196

SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties. The FADS2 inhibitor SC26196 reduced PBMC, but not Jurkat cell, proliferation suggesting PUFA synthesis is involved in regulating mitosis in PBMCs.

Product Specifications

CAS Number

218136-59-5

Purity

>98% (HPLC)

Solubility

DMSO:4mg/ml (9.44 Mm; Need ultrasonic)

Smiles

C1CN (CCN1CCCC (C#N) (C2=CC=CC=C2) C3=CC=CC=C3) N=CC4=CN=CC=C4

Molecular Formula

C27H29N5

Molecular Weight

423.55

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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