SC-26196
SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties. The FADS2 inhibitor SC26196 reduced PBMC, but not Jurkat cell, proliferation suggesting PUFA synthesis is involved in regulating mitosis in PBMCs.
Product Specifications
CAS Number
218136-59-5
Purity
>98% (HPLC)
Solubility
DMSO:4mg/ml (9.44 Mm; Need ultrasonic)
Smiles
C1CN (CCN1CCCC (C#N) (C2=CC=CC=C2) C3=CC=CC=C3) N=CC4=CN=CC=C4
Molecular Formula
C27H29N5
Molecular Weight
423.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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