GOAT ANTI HUMAN SURVIVIN (C-TERMINAL)

Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.<br>Shelf Life: 18 months from date of despatch.

This item specifically recognises an epitope within the C-terminal (CT) region of human Survivin, otherwise known as TIAP/BIRC5, a novel inhibitor of apoptosis (IAP) protein, and component of the chromosomal passenger complex, which plays a key role in the regulation of mitosis. <br> <br>Survivin is only expressed during the G2-M cell cycle phase, and is predominantly expressed in foetal tissues, and in many human cancers, including adenocarcinomas and high-grade lymphomas. The lack of survivin expression by normal non-malignant cells, makes survivin an important therapeutic target for cancer.

[baculoviral IAP repeat-containing protein 5 isoform 2; Baculoviral IAP repeat-containing protein 5; baculoviral IAP repeat-containing protein 5; apoptosis inhibitor 4; apoptosis inhibitor survivin; survivin variant 3 alpha; baculoviral IAP repeat containing 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin]