Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Dabrafenib Mesylate

Dabrafenib Mesylate is a B-Raf inhibitor (IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively) .In human endothelial cells, Dabrafenib inhibits the release of HMGB1 and down-regulates the HMGB1-dependent inflammatory response by enhancing the expression of cell adhesion molecules (CAM) .

Product Specifications

CAS Number

1195768-06-9

Product Name Alternative

GSK2118436 Mesylate, GSK 2118436B

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO:34 mg/mL (55.22 mM)

Smiles

CS (O) (=O) =O.CC (C) (C) C1=NC (=C (S1) C1=NC (N) =NC=C1) C1=C (F) C (NS (=O) (=O) C2=C (F) C=CC=C2F) =CC=C1

Molecular Formula

C24H24F3N5O5S3

Molecular Weight

615.67

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Calcium Chloride, 500g
PC0904-500g 500 g

Calcium Chloride, 500g

Sign In for Pricing
View Details
Retinol Binding Protein-1 (RBP/872), CF740 conjugate, 0.1mg/mL
BNC740872-500 1x 500 µL

Retinol Binding Protein-1 (RBP/872), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
(R)-Jorgensen-Hayashi Catalyst
TRC-J212020-500MG 500 mg

(R)-Jorgensen-Hayashi Catalyst

Sign In for Pricing
View Details
PE/Cyanine5.5 Anti-Mouse CD11a Antibody[FD441.8]
E-AB-F1033I-01 50 Tests

PE/Cyanine5.5 Anti-Mouse CD11a Antibody[FD441.8]

Sign In for Pricing
View Details
PE/Cyanine5.5 Anti-Mouse CD11a Antibody[FD441.8]
E-AB-F1033I-02 100 Tests

PE/Cyanine5.5 Anti-Mouse CD11a Antibody[FD441.8]

Sign In for Pricing
View Details
PE/Cyanine5.5 Anti-Mouse CD11a Antibody[FD441.8]
E-AB-F1033I-03 2x 100 Tests

PE/Cyanine5.5 Anti-Mouse CD11a Antibody[FD441.8]

Sign In for Pricing
View Details