RABBIT ANTI DISC1

Store at 4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.<br>Shelf Life: 18 months from date of despatch.

This item recognises disrupted in schizophrenia 1 (DISC1), 93kD protein located in the nucleus, cytoplasm and mitochondria. The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. <br> <br>In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1;11) (q42.1;q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition.This product has been found suitable for immunocytochemistry (ICC) at a concentration of 5ug/ml.

[disrupted in schizophrenia 1 protein isoform Lv; Disrupted in schizophrenia 1 protein; disrupted in schizophrenia 1 protein; disrupted in schizophrenia 1]