RABBIT ANTI HUMAN XEDAR

Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.<br>Shelf Life: 18 months from date of despatch.

This item detects human X-linked ectodermal dysplasia receptor (XEDAR), a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. <br>Two predominant isoforms of XEDAR exist; XEDAR-s and XEDAR-L, produced by alternative splicing.

[tumor necrosis factor receptor superfamily member 27 isoform 1; Tumor necrosis factor receptor superfamily member 27; tumor necrosis factor receptor superfamily member 27; EDA-A2 receptor; X-linked ectodysplasin-A2 receptor; tumor necrosis factor receptor superfamily member XEDAR; ectodysplasin A2 receptor; X-linked ectodysplasin-A2 receptor; EDA-A2 receptor]