HJC0197
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2) . In the presence of an equal concentration of cAMP, HJC0197 (25 μM) also inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM.
Product Specifications
CAS Number
1383539-73-8
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (147.30 mM)
Smiles
Cc1ccc (C) c (CSc2nc (C3CCCC3) c (C#N) c (=O) [nH]2) c1
Molecular Formula
C19H21N3OS
Molecular Weight
339.45
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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