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HJC0197

HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2) . In the presence of an equal concentration of cAMP, HJC0197 (25 μM) also inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM.

Product Specifications

CAS Number

1383539-73-8

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (147.30 mM)

Smiles

Cc1ccc (C) c (CSc2nc (C3CCCC3) c (C#N) c (=O) [nH]2) c1

Molecular Formula

C19H21N3OS

Molecular Weight

339.45

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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