Mal-amido-PEG4-NHS ester
Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Product Specifications
CAS Number
756525-99-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (194.74 mM)
Smiles
O=C (CCN1C (=O) C=CC1=O) NCCOCCOCCOCCOCCC (=O) ON1C (=O) CCC1=O
Molecular Formula
C22H31N3O11
Molecular Weight
513.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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