Metoprine
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.In mammals, histamine N-methyltransferase (HMT) is the sole enzyme responsible for degrading histamine in the brain. Metoprine, one of the most potent HMT inhibitors, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Consequently, this compound can be a candidate for a prototype of drugs for the treatment of METH overdose.
Product Specifications
CAS Number
7761-45-7
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 20.83 mg/mL (77.40 mM)
Smiles
Cc1nc (N) nc (N) c1-c1ccc (Cl) c (Cl) c1
Molecular Formula
C11H10Cl2N4
Molecular Weight
269.13
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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