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Metoprine

Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.In mammals, histamine N-methyltransferase (HMT) is the sole enzyme responsible for degrading histamine in the brain. Metoprine, one of the most potent HMT inhibitors, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Consequently, this compound can be a candidate for a prototype of drugs for the treatment of METH overdose.

Product Specifications

CAS Number

7761-45-7

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 20.83 mg/mL (77.40 mM)

Smiles

Cc1nc (N) nc (N) c1-c1ccc (Cl) c (Cl) c1

Molecular Formula

C11H10Cl2N4

Molecular Weight

269.13

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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