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A 425619

A 425619 is a potent TRPV1 antagonistsystemic administration of the TRPV1 antagonist, A-425619, reversed the decrease in digging behavior induced by CFA injection, further confirming the role of TRPV1, expressed by knee neurons, in acute inflammatory joint pain.

Product Specifications

CAS Number

581809-67-8

Product Name Alternative

1- (4- (TRIFLUOROMETHYL) BENZYL) -3- (ISOQUINOLIN-5-YL) UREA

Purity

>98% (HPLC)

Solubility

DMSO:34.5 mg/mL (100 mM; Need ultrasonic)

Smiles

FC (F) (F) c1ccc (CNC (=O) Nc2cccc3cnccc23) cc1

Molecular Formula

C18H14F3N3O

Molecular Weight

345.33

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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