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BC-1382

BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction (IC50 of 5 nM) .BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS) - and Pseudomonas aeruginosa-induced lung inflammation.

Product Specifications

CAS Number

1013753-99-5

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 125 mg/mL (272.00 mM)

Smiles

COc1ccccc1CNC (=O) [C@H] (C) NC (=O) C1CCN (CC1) S (=O) (=O) c1ccccc1

Molecular Formula

C23H29N3O5S

Molecular Weight

459.56

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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