BC-1382
BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction (IC50 of 5 nM) .BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS) - and Pseudomonas aeruginosa-induced lung inflammation.
Product Specifications
CAS Number
1013753-99-5
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (272.00 mM)
Smiles
COc1ccccc1CNC (=O) [C@H] (C) NC (=O) C1CCN (CC1) S (=O) (=O) c1ccccc1
Molecular Formula
C23H29N3O5S
Molecular Weight
459.56
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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