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TAT

TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins[1].TAT (YGRKKRRQRRR) represents amino acids 47-57 of the human immunodeficiency virus type I (HIV-1) TAT protein. The positively charged protein transduction domain of the HIV-1 TAT protein (TAT-PTD; residues 47-57 of TAT) rapidly translocates across the plasma membrane of living cells. TAT (YGRKKRRQRRR; TAT-PTD) can cross the hydrophobic lipid bilayer of a cell membrane simply by passive diffusion.

Product Specifications

CAS Number

191936-91-1

Field of Research

Signal Transduction

Purity

>98% (HPLC)

Solubility

H2O

Smiles

NCCCC[C@H] (NC (=O) [C@H] (CCCNC (N) =N) NC (=O) CNC (=O) [C@@H] (N) Cc1ccc (O) cc1) C (=O) N[C@@H] (CCCCN) C (=O) N[C@@H] (CCCNC (N) =N) C (=O) N[C@@H] (CCCNC (N) =N) C (=O) N[C@@H] (CCC (N) =O) C (=O) N[C@@H] (CCCNC (N) =N) C (=O) N[C@@H] (CCCNC (N) =N) C (=O) N[C@@H] (CCCNC (N) =N) C (O) =O

Molecular Formula

C64H118N32O14

Molecular Weight

1559.83

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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