MOUSE ANTI HUMAN C6
Product Specifications
CAS Number
9007-83-4
Gene Name
[C6]
NCBI Gene ID
729
Storage Conditions
Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.<br>Shelf Life: 18 months from date of despatch.
Specificity
This item recognises complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection.
<br>
<br>This item recognises MAC.
Other Gene Names
[C6; C6]
Short Name
[C6]
Other Product Names
[complement component C6; Complement component C6; complement component C6; complement component 6]
NCBI GI Number
169636415
NCBI Accession Number
NP_000056.2
NCBI GB Accession Number
NM_000065.3
Uniprot Accession Number
P13671
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
