AMG-47a
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.
Product Specifications
CAS Number
882663-88-9
Purity
>98% (HPLC)
Solubility
DMSO:34 mg/mL (63.48 mM)
Smiles
Cc1ccc (C (=O) Nc2cccc (C (F) (F) F) c2) cc1-c1ccc2nc (NCCN3CCOCC3) ncc2c1
Molecular Formula
C29H28F3N5O2
Molecular Weight
535.56
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-methyl-3-[2- (2-morpholin-4-ylethylamino) quinazolin-6-yl]-N-[3- (trifluoromethyl) phenyl]benzamide
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