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AMG-47a

AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.

Product Specifications

CAS Number

882663-88-9

Purity

>98% (HPLC)

Solubility

DMSO:34 mg/mL (63.48 mM)

Smiles

Cc1ccc (C (=O) Nc2cccc (C (F) (F) F) c2) cc1-c1ccc2nc (NCCN3CCOCC3) ncc2c1

Molecular Formula

C29H28F3N5O2

Molecular Weight

535.56

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4-methyl-3-[2- (2-morpholin-4-ylethylamino) quinazolin-6-yl]-N-[3- (trifluoromethyl) phenyl]benzamide

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