What is the catalog number for Ombitasvir?

The catalog number for Ombitasvir is orb1220539.

What sizes are available for Ombitasvir?

Ombitasvir is available in the following size(s): 1 g, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg.

How many pack sizes does Ombitasvir come in?

Ombitasvir is available in 7 different pack sizes.

Is Ombitasvir in stock?

Ombitasvir is currently made to order / not held in immediate stock. Contact us for lead time.

Ombitasvir

Ombitasvir is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) .with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5 and 366 pM against genotype 6a. (In Vitro) :Ombitasvir is active against the genotype 2a JFH-1 replicon, with an EC50 of 0.82 pM, and the EC50s of ombitasvir are 42 pM and 68 pM against the L28 and F28 variants of this genotype 6a replicon, respectively. In GT1a, variants M28V, L31V, and H58D confers 58- to 243-fold resistance to Ombitasvir. Single variants M28T, Q30R, and Y93C/S confers 800- to 8965-fold resistance, while Y93H/N confers >40000-fold resistance to Ombitasvir.

Product Specifications

CAS Number

1258226-87-7

Product Name Alternative

ABT-267

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO:33 mg/mL (36.91 mM)

Smiles

COC (=O) N[C@@H] (C (C) C) C (=O) N1CCC[C@H]1C (=O) Nc1ccc (cc1) [C@@H]1CC[C@H] (N1c1ccc (cc1) C (C) (C) C) c1ccc (NC (=O) [C@@H]2CCCN2C (=O) [C@@H] (NC (=O) OC) C (C) C) cc1