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Capsazepine

Capsazepine is an antagonist of TRPV1 receptor (IC50 : 562 nM) . Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is therefore considered to be a capsaicin antagonist.

Product Specifications

CAS Number

138977-28-3

Purity

>98% (HPLC)

Solubility

DMSO:50 mg/mL (132.66 mM)

Smiles

Oc1cc2CCCN (Cc2cc1O) C (=S) NCCc1ccc (Cl) cc1

Molecular Formula

C19H21ClN2O2S

Molecular Weight

376.9

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N-[2- (4-Chlorophenyl) ethyl]-1345-tetrahydro-78-dihydroxy-2H-2-benzazepine-2-carbothioamide

Available Sizes

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