MK-0608

MK-0608 is a potent and orally bioavailable inhibitor of HCV replication in vitro with an EC50 of 0.3 μM (EC90=1.3 μM) in the subgenomic-replicon assay[1].

Product Specifications

CAS Number

[443642-29-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HCV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mk-0608.html

Purity

99.81

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OC[C@@H]1[C@@H](O)[C@](O)(C)[C@H](N2C=CC3=C2N=CN=C3N)O1

Molecular Formula

C12H16N4O4

Molecular Weight

280.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Carroll SS, et al. Robust antiviral efficacy upon administration of a nucleoside analog to hepatitis C virus-infected chimpanzees. Antimicrob Agents Chemother. 2009 Mar;53 (3) :926-34.