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Wilforine

Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect which might be mediated by down-regulation of the expression of inflammatory factors TNF-α IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.

Product Specifications

CAS Number

11088-09-8

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (57.61 mM)

Smiles

C[C@@H] (CCc (nccc1) c1C (OC[C@@] (C) ([C@@H] ([C@H]1OC (C) =O) [C@H] ([C@H]2OC (C) =O) OC (C) =O) O[C@@]1 ([C@] (C) ([C@H] ([C@@H]1OC (c3ccccc3) =O) O3) O) [C@]2 (COC (C) =O) [C@H]1OC (C) =O) =O) C3=O

Molecular Formula

C43H49NO18

Molecular Weight

867.85

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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