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Escin IA; Aescin IA

Escin IA is a triterpene saponin isolated from horse chestnut which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression.

Product Specifications

CAS Number

123748-68-5

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (88.40 mM)

Smiles

C/C=C (\C) /C (=O) O[C@H]1[C@@H] ([C@@]2 ([C@@H] (C[C@@]3 (C (=CC[C@H]4[C@]3 (CC[C@@H]5[C@@]4 (CC[C@@H] ([C@]5 (C) CO) O[C@H]6[C@@H] ([C@H] ([C@@H] ([C@H] (O6) C (=O) O) O[C@H]7[C@@H] ([C@H] ([C@@H] ([C@H] (O7) CO) O) O) O) O) O[C@H]8[C@@H] ([C@H] ([C@@H] ([C@H] (O8) CO) O) O) O) C) C) [C@@H]2CC1 (C) C) C) O) CO) OC (=O) C

Molecular Formula

C55H86O24

Molecular Weight

1131.3

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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