L-368,899 hydrochloride
L-368,899 hydrochloride is a potent, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 is less active on VP receptor in human liver and kidney, rat liver and kidney (IC50, 510 nM, 960 nM, 890 nM, 2400 nM, respectively) .
Product Specifications
CAS Number
160312-62-9
Purity
>98% (HPLC)
Solubility
DMSO : 130 mg/mL (219.88 mM; Need ultrasonic)
Smiles
O=C (NC1[C@@] (C2 (C) C) (CS (=O) (N3CCN (C4=CC=CC=C4C) CC3) =O) CC[C@]2 ([H]) C1) [C@H] (N) CCS (=O) (C) =O.[H]Cl
Molecular Formula
C??H??ClN?O?S?
Molecular Weight
591.23
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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