Pemigatinib (INCB054828)
Pemigatinib (INCB054828) is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.
Product Specifications
CAS Number
1513857-77-6
Product Name Alternative
INCB054828
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : 25 mg/mL (51.28 mM; ultrasonic and warming and heat to 60°C)
Smiles
CCN (C (N (C (C (F) =C (OC) C=C1OC) =C1F) C2) =O) C (C2=CN3) =C4C3=NC (CN5CCOCC5) =C4
Molecular Formula
C??H??F?N?O?
Molecular Weight
487.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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