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LC3-mHTT-IN-AN1

LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

Product Specifications

CAS Number

486443-73-6

Field of Research

Stem Cell & Developmental Biology

Purity

>98% (HPLC)

Solubility

DMSO : 125 mg/mL (304.11 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble)

Smiles

BrC1=CC=C (C/2=C1) NC (C2=C/C3=CC (Br) =C (C (O) =C3) O) =O

Molecular Formula

C??H?Br?NO?

Molecular Weight

411.04

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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