LIN28 inhibitor LI71
LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM.LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells.
Product Specifications
CAS Number
1357248-83-9
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (298.15 mM)
Smiles
O=C (O) C1=CC=C ([C@@H]2NC3=C (C=CC=C3OCC) [C@@]4 ([H]) [C@]2 ([H]) CC=C4) C=C1
Molecular Formula
C21H21NO3
Molecular Weight
335.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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