Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PF-06446846

PF 06446846 is a potent and selective PCSK9 inhibitor PF-06446846 reduces plasma PCSK9 and total cholesterol levels in rats following oral dosing. PF-06446846 is highly selective for the inhibition of PCSK9 translation. The mechanism of action employed by PF-06446846 reveals a previously unexpected tunability of the human ribosome that allows small molecules to specifically block translation of individual transcripts.

Product Specifications

CAS Number

1632250-49-7

Purity

>98% (HPLC)

Smiles

Clc1cccnc1N ([C@@H]1CCCNC1) C (=O) c1ccc (cc1) -n1nnc2cccnc12

Molecular Formula

C22H20ClN7O

Molecular Weight

433.9

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Febuxostat Acyl-β-D-glucuronide
011937 2.5 mg

Febuxostat Acyl-β-D-glucuronide

Sign In for Pricing
View Details
COPB2 (NM_004766) Human Over-expression Lysate
LC417762 20 µg

COPB2 (NM_004766) Human Over-expression Lysate

Sign In for Pricing
View Details
Recombinant Protease HtpX (htpX)
MBS1056462 Inquire

Recombinant Protease HtpX (htpX)

Sign In for Pricing
View Details
TrkB Protein, Mouse, Recombinant (His Tag)
MBS8122553-01 0.05 mg

TrkB Protein, Mouse, Recombinant (His Tag)

Sign In for Pricing
View Details
TrkB Protein, Mouse, Recombinant (His Tag)
MBS8122553-02 5x 0.05 mg

TrkB Protein, Mouse, Recombinant (His Tag)

Sign In for Pricing
View Details
Chicken Chromodomain-helicase-DNA-binding protein 6 (CHD6) ELISA Kit
MBS7212291-01 48 Well

Chicken Chromodomain-helicase-DNA-binding protein 6 (CHD6) ELISA Kit

Sign In for Pricing
View Details