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Nourseothricin sulfate

Nourseothricin sulfate is a broad-spectrum antibiotic, and inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi .Renal handling of Nourseothricin is characterized in experiments on renal cortical slices under various experimental conditions. Following administration in vivo the renal tubular transport system for organic anions (p-aminohippurate, PAH) is not influenced by Nourseothricin. There is a high degree of accumulation of Nourseothricin in renal cortical slices. In contrast to PAH accumulation there is no influence of nitrogen atmosphere, simultaneous administration of PAH, probenecid or trishydroxyaminomethane on Nourseothricin accumulation. Age dependent differences in Nourseothricin accumulation does not exist.

Product Specifications

CAS Number

96736-11-7

Product Name Alternative

Streptothricin sulfate

Purity

>98% (HPLC)

Solubility

H2O:250 mg/mL (183.90 mM; Need ultrasonic)

Smiles

O=S (=O) (O) O.NCCC[C@H] (N) CC (=O) N[C@@H]3[C@H] (O) [C@@H] (OC (N) =O) [C@@H] (CO) O[C@H]3NC1=N[C@@H]2C (=O) NC[C@@H] (O) [C@H]2N1.NCCC[C@H] (N) CC (=O) NCCC[C@H] (N) CC (=O) NCCC[C@H] (N) CC (=O) N[C@@H]3[C@H] (O) [C@@H] (OC (N) =O) [C@@H] (CO) O[C@H]3NC=1N[C@@H]2[C@H] (O) CNC (=O) [C@H]2N=1

Molecular Formula

C50H94N20O22S

Molecular Weight

1359.47

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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