LY 345899
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1) .
Product Specifications
CAS Number
10538-99-5
Purity
>98% (HPLC)
Solubility
DMSO:125 mg/mL (265.16 mM; Need ultrasonic)
Smiles
Nc1nc (=O) c2N3C (CN (C3=O) c3ccc (cc3) C (=O) N[C@@H] (CCC (O) =O) C (O) =O) CNc2[nH]1
Molecular Formula
C20H21N7O7
Molecular Weight
471.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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