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MF-438

MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1) . In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.

Product Specifications

CAS Number

921605-87-0

Purity

>98% (HPLC)

Solubility

DMSO:62.5 mg/mL (148.30 mM; Need ultrasonic)

Smiles

Cc1nnc (s1) -c1ccc (nn1) N1CCC (CC1) Oc1ccccc1C (F) (F) F

Molecular Formula

C19H18F3N5OS

Molecular Weight

421.44

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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