Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

MYCi975

MYCi975 is an orally active inhibitor of MYC.MYCi975 inhibits P493-6, MV411, SK-N-B2 cells viability in an MYC-dependent manner (IC50s of 3.7, 3.9, 6.4 μM, respectively) [1].The initial lead, MYC inhibitor 361 (MYCi361), suppressed in vivo tumor growth in mice, increased tumor immune cell infiltration, upregulated PD-L1 on tumors, and sensitized tumors to anti-PD1 immunotherapy. However, 361 demonstrated a narrow therapeutic index. An improved analog, MYCi975 showed better tolerability.

Product Specifications

CAS Number

2289691-01-4

Product Name Alternative

NUCC-0200975

Purity

>98% (HPLC)

Solubility

DMSO:247 mg/mL (440.05mM)

Smiles

Cn1nc (cc1-c1ccc (OCc2ccc (Cl) cc2) c (-c2ccc (Cl) c (c2) C (F) (F) F) c1O) C (F) (F) F

Molecular Formula

C25H16Cl2F6N2O2

Molecular Weight

561.3

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rat Cyclin D2 CCND2 ELISA Kit
BG-RAT10556 1 Each

Rat Cyclin D2 CCND2 ELISA Kit

Sign In for Pricing
View Details
Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit
MBS2703888-01 24 Strip Well

Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit

Sign In for Pricing
View Details
Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit
MBS2703888-02 48 Well

Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit

Sign In for Pricing
View Details
Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit
MBS2703888-03 96 Well

Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit

Sign In for Pricing
View Details
Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit
MBS2703888-04 5x 96 Well

Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit

Sign In for Pricing
View Details
Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit
MBS2703888-05 10x 96 Well

Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit

Sign In for Pricing
View Details