Sodium Oxamate
Sodium Oxamate is an LDH inhibitor. Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the CDK1/cyclin B1 pathway and promotes apoptosis through enhancement of mitochondrial ROS generation.It inhibits L (+) -lactate dehydrogenase and derails the entire gluconeogenic pathway.NETosis and lactate accumulation during LPS induced sepsis in mice was inhibited by sodium oxamate, LDH inhibitor.
Product Specifications
CAS Number
565-73-1
Product Name Alternative
SO, oxamate sodium, Aminooxoacetic acid sodium salt, Oxamic acid sodium salt
Purity
>98% (HPLC)
Solubility
In Vitro: H2O : 12.5 mg/mL (112.58 mM)
Smiles
[Na+].NC (=O) C ([O-]) =O
Molecular Formula
C2H2NNaO3
Molecular Weight
111.03
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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