MSAB
MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.MSAB act against Wnt/β-catenin signaling and identified as a selective inhibitor of Wnt/β-catenin signaling. MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes. might represent an effective therapeutic strategy for cancers addicted to the Wnt/β-catenin signaling pathway.
Product Specifications
CAS Number
173436-66-3
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (818.73 mM)
Smiles
COC (=O) c1cccc (NS (=O) (=O) c2ccc (C) cc2) c1
Molecular Formula
C15H15NO4S
Molecular Weight
305.35
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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