AA147
AA147 is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity.
Product Specifications
CAS Number
393121-74-9
Product Name Alternative
ATF6-activator-147
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (195.84 mM)
Smiles
Cc1ccc (O) c (NC (=O) CCc2ccccc2) c1
Molecular Formula
C16H17NO2
Molecular Weight
255.31
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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