2,3-Dihydrobenzofuran

2,3-Dihydrobenzofuran is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran can be used as a biopesticide. 2,3-dihydrobenzofuran is a member of the class of 1-benzofurans that is the 2,3-dihydroderivative of benzofuran. It has a role as a metabolite.The in vitro inhibition of acetylcholinesterase was increased with the concentration of Coumaran in the housefly (head and thorax) homogenate. Activity of acetylcholinesterase in insects exposed to LC25, LC50, and LC90 doses of Coumaran was markedly inhibited in dose-dependent studies in the head and thorax of housefly and homogenate of stored grain insect pests. The in vivo enzyme inhibition was dose dependent and correlated with the knockdown effect measured at 45 min of exposure in the fumigation bioassay.