GPNA hydrochloride
GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2 (SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT) . GPNA hydrochloride also inhibits Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2.GPNA (10-1000 μM; 48 hours) induces a dose-dependent to reduce of cell viability in A549 cells.
Product Specifications
CAS Number
67953-08-6
Purity
>98% (HPLC)
Solubility
DMSO:124 mg/mL (408.3 mM)
Smiles
Cl.N[C@@H] (CCC (=O) Nc1ccc (cc1) [N+] ([O-]) =O) C (O) =O
Molecular Formula
C11H14ClN3O5
Molecular Weight
303.7
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
136506 50 µg
Tubulin, gamma (TUBG, TUBG1, TUBGCP1, Tubulin gamma Chain, TUBG1, GCP 1) discontinued
Sign In for Pricing
View Details 
FZC90710-01 100 mg
4-Amino-1- (propan-2-yl) -1H-pyrazole-5-carboxylic acid hydrochloride
Sign In for Pricing
View Details FZC90710-02 1 g
4-Amino-1- (propan-2-yl) -1H-pyrazole-5-carboxylic acid hydrochloride
Sign In for Pricing
View Details