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12-O-Methylcarnosic acid

12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM.12-O-Methylcarnosic acid has antioxidant activity, it is effective preventing gastric lesions. 12-O-Methylcarnosic acid can suppress melanin production with downregulation of tyrosinase expression in HMV-II melanoma cells.12-O-Methylcarnosic acid may have anti-diabetic activity, it is able to significantly activate peroxisome proliferator-activated receptor (PPAR) γ.

Product Specifications

CAS Number

62201-71-2

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (144.32 mM)

Smiles

[H][C@@]12CCc3cc (C (C) C) c (OC) c (O) c3[C@]1 (CCCC2 (C) C) C (O) =O

Molecular Formula

C21H30O4

Molecular Weight

346.46

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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