MID-1
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
Product Specifications
CAS Number
312608-54-1
Purity
>98% (HPLC)
Solubility
DMSO:31.25 mg/mL (106.55 mM; Need ultrasonic)
Smiles
CCOc1ccc (cc1) C (=O) Nc1ncc (s1) [N+] ([O-]) =O
Molecular Formula
C12H11N3O4S
Molecular Weight
293.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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