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MID-1

MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.

Product Specifications

CAS Number

312608-54-1

Purity

>98% (HPLC)

Solubility

DMSO:31.25 mg/mL (106.55 mM; Need ultrasonic)

Smiles

CCOc1ccc (cc1) C (=O) Nc1ncc (s1) [N+] ([O-]) =O

Molecular Formula

C12H11N3O4S

Molecular Weight

293.3

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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